Research Results
Mood Disorders and Trauma – What are the Associations?
Yael Dvir M.D., Michael Hill B.S, Steven M Hodge M.A., Jean A Frazier M.D.
Results of the study suggest that a careful clinical evaluation that uses standardized tools can help differentiate between bipolar disorder and other mood disorders in youth. We found that there were higher rates of bipolar disorder and schizophrenia in families of children who have a history of bipolar disorder and trauma.
Taken together, these preliminary results suggest potential biological and genetic vulnerabilities which may predispose children to develop specific mood disorders under certain circumstances; the ability to identify these children early on could change their treatment and possibly their future.
The Pediatric Imaging, Neurocognition, and Genetics (PING)
The main objective of the multi-site Pediatric Imaging, Neurocognition, and Genetics (PING) study was to create a large repository of standardized measurements of behavioral and imaging phenotypes accompanied by whole genome genotyping acquired from typically-developing children across a wide age range (3 to 20 years). This cross-sectional study produced sharable data from 1493 children, and these data have been described in several publications focusing on brain and cognitive development. Researchers may gain access to these data by applying for an account at the NIMH Data Archive (NDA) by creating an account and filing a Data Use Agreement.